Platform Technology​

FLAGSHIP PRODUCT MNM96: MECHANISM OF ACTION

Innovative cell killing approach by molecular nanomachines.

MNM96 technology follows the discovery of synthetic machines building upon Nobel Prize discovery.  Upon light activation, the rotor part of the molecule rotates unidirectionally against the stator part of the molecule around the rotor-to-stator connecting double bond axis. The unidirectional rotation is governed by a cis-trans photoisomerization cycle and thermal ratcheting steps. The photoisomerization cycle is fast, allowing the motor to rotate at approximately 3×106 revolutions per second. We have optimized a new generation of light-activated unidirectional molecular nanomachines that can perforate cellular membranes and cause cell death via necrosis. 

FLAGSHIP PRODUCT MNM96: MECHANISM OF ACTION

Innovative cell killing approach by molecular nanomachines.

MNM96 technology follows the discovery of synthetic machines building upon Nobel Prize discovery.  Upon light activation, the rotor part of the molecule rotates unidirectionally against the stator part of the molecule around the rotor-to-stator connecting double bond axis. The unidirectional rotation is governed by a cis-trans photoisomerization cycle and thermal ratcheting steps. The photoisomerization cycle is fast, allowing the motor to rotate at approximately 3×106 revolutions per second. We have optimized a new generation of light-activated unidirectional molecular nanomachines that can perforate cellular membranes and cause cell death via necrosis. 

CLINICAL USE : Easy-to-use gel (light-activated molecule)

Diagnosis:
Previously diagnosed patient arrives for treatment
Administration:
Dermatologist applies a thin layer to lesion surface
Incubation Time:
Remaining gel wiped off

Treatment:
Treated area exposed to light to activate the molecule

 

TECHNOLOGY ADVANTAGES

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